Medical Chemistry and Biochemistry

This publication is intended mainly for students of medicine studying at the UPJŠ in Košice, Faculty of Medicine. The textbook covers the basic knowledge of selected topics of general, physical, inorganic, organic and bioorganic chemistry required for successful completion of the course of Medical Chemistry. Knowledge of the structures and functions of chemical substances and compounds, as well as their interactions and factors of surroundings influencing those interactions is very important for next study medical biochemistry incoming physicians. For better and easier understanding is the text appropriately supplemented with figures, tables, and numerous of chemical schemes. The separate part of this publication presents the chemistry of the most important dental materials used in clinical practise of future dentists, including the properties of metals, polymers and impression materials.

The laboratory manuals are developed to the foreign students of medicine for practical laboratory exercise and verification of knowledge from medical biochemistry. Exercises are arranged into weeks in winter term (WT) and summer term (ST), like it is in Syllabus of Lectures and practical exercises (WT, ST). Students can apply their manual skill in performing of the experiments, and also train their ability in evaluation of results and making of diagnoses.

Revised and supplemented first published version “Practical exercises from biochemistry”. Authors: Tomečková V., Kron I., Mareková M., Pavol Jozef Šafárik University in Košice, Košice 2011, ISBN 978-80-7097-874-0.

Proper administration of individual medications and reagents is of the upmost importance in the clinical practice of future doctors. It can be affected by age, body weight, kidney and liver health, and other health conditions. Subject Medical Chemistry is therefore an essential part of the theoretical education at medical faculties. The basics for the successful completion of the course are also basic chemistry calculations including solution preparation, stoichiometric calculations, pH calculations (including buffers) and spectrophotometric calculations. In addition to brief theoretical introductions, the material also contains a series of examples for practice, in order to help students in repeating and preparing for the exam from Medical Chemistry.

Practical exercises from the subject Dental Materials contain selected experimental tasks that enable students to become familiar with the chemical properties of materials commonly used in dentistry. They contribute to a better understanding of the properties of e.g., hydroxyapatite, metal corrosion and other properties of elements contained in dental materials. Separate attention is paid to dental plaster - its preparation and properties.

The laboratory manuals are developed to the foreign students of medicine for practical laboratory exercise and verification of knowledge from medical biochemistry. Exercises are gathered into bigger groups by topics. Exercises are arranged into weeks, in summer term (ST) and winter term (WT), like it is in Syllabus of Lectures and practical exercises (ST, WT). Students can apply their manual skill in performing of the experiments, and also train their ability in evaluation of results.

First published: Tomečková V., Kron I., Mareková M.: Practical exercises from biochemistry, Univerzita Pavla Jozefa Šafárika v Košiciach, Košice 2011, ISBN 978-80-7097-874-0.

Practical exercises from Medical Chemistry is a set of experimental exercises designed for a better understanding of the subject. Laboratory manuals for the practical exercises are arranged into weeks according to the syllabus (WT) and contain theoretical introduction as well as experimental procedures for each exercise. Published material represents an effective instrument for understanding of the basic principles of Medical Chemistry.

Revised and supplemented first published version “Practical exercises from Medical Chemistry”. Authors: Stupák M., Rabajdová M., Mašlanková J., Urban P., Tomečková V., Mareková M.

Clinical Biochemistry is an extension of the basic rate of Medical Biochemistry from 2nd year. It is a highly applied medical biochemistry, which provides teachers - doctors with experience in clinical biochemistry. The aim of the course is in the form of lectures and seminars to provide information on biochemical investigation methods for selected diseases and diagnostic options refer to the relationship between metabolism and laboratory values in model tests patients align tests with monitoring therapy and selecting the most appropriate investigative methods in relation to the expected diagnosis. Correct indication and interpretation of clinical biochemistry tests is an important part of a physician's daily work.

The electronic textbook of Clinical Biochemistry – selected chapters (2nd edition) has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed study of laboratory methods and their use in diagnostic and monitoring algorithms. The textbook focuses on disorders of water-ion and acid-base balance disorders, and basic diagnostics of diseases of selected organs.

ISBN 978-80-8152-937-5 (e-publication); www.unibook.upjs.sk; https://unibook.upjs.sk/img/cms/2020/lf/clinical-biochemistry.pdf

The subject Dental Materials represents an introduction to the study of the chemical properties of materials routinely used in dentistry. The lectures are focused on selected parts of the study of metals, including noble metals and their alloys. Furthermore, attention is focused on ceramic materials, on dental cements, as well as on polymerization and substances resulting from polymerization and used in dentistry for both restorative and prosthetic purposes.

Medical Biochemistry has an irreplaceable role in study of General Medicine. The students should learn about biochemical reactions in all living systems, especially in the human body. The knowledge will help them later to diagnose and treat many diseases correctly. In firsts semester is study concentrated to metabolic processes connected with metabolism of nutrients (e.g. saccharides, lipids, proteins, nucleic acids). In second semester is teaching focused to study metabolism of organs (e.g. liver, kidney, muscles, hard tissue, skin), chemical communications and introduction to Clinical Biochemistry.