Medical Biochemistry has an irreplaceable role in study of General Medicine. The students should learn about biochemical reactions in all living systems, especially in the human body. The knowledge will help them later to diagnose and treat many diseases correctly. In firsts semester is study concentrated to metabolic processes connected with metabolism of nutrients (e.g. saccharides, lipids, proteins, nucleic acids). In second semester is teaching focused to study metabolism of organs (e.g. liver, kidney, muscles, hard tissue, skin), chemical communications and introduction to Clinical Biochemistry.
Authors offer lectures of medical biochemistry. Here described themes include:
| 2. GM – Winter term | 2. GM – Summer term |
| Cell biochemistry | Amino acid metabolism I |
| Enzymes and their role in metabolism | Amino acid metabolism II |
| Coenzymes – structure and function | Metabolism of nucleotides |
| Krebs cycle and Respiratory chain | Imtermediary metabolism |
| Metabolism of glucose | Replication and transcription |
| Metabolism of glycogene and Pentose phosphate pathway | Translation and regulation of gene expression |
| Metabolism of derivatives monosaccharides, GAG and complex saccharides | Blood Biochemistry |
| Metabolism of FA, TAG and PL | Chemical communications in living systems |
| Metabolism of complex lipids | Metabolism of the Liver and Xenobiochemistry |
| Metabolism of steroids | Metabolism of kidney |
| Oxidation stress | Metabolism of minerals and trace elements |
| Metabolism of hard tissue | |
| Specialised metabolic pathway of selected tissues | |
| Biochemistry and pathobiochemistry of digestion and nutrition | |
| Clinical biochemistry |
| Attachment | Date | Size | Availability [?] | Clinically sensitive [?] | Licence | |
|---|---|---|---|---|---|---|
| Cell Biochemistry | 11.10.2022 | 4.33 MB | faculty member | – |  |
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| Enzymes I | 11.10.2022 | 3.43 MB | faculty member | – | |
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| Enzymes II | 11.10.2022 | 6.39 MB | faculty member | – | |
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| Metabolism of saccharides I | 25.10.2021 | 3.91 MB | faculty member | – | |
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| Metabolism of saccharides II | 25.10.2021 | 2.5 MB | faculty member | – | |
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| Metabolism of saccharides III | 25.10.2021 | 2.99 MB | faculty member | – | |
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| The Citric Acid Cycle | 25.10.2021 | 2.68 MB | faculty member | – | |
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| The Respiratory Chain | 25.10.2021 | 2.63 MB | faculty member | – | |
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| Degradation of lipids | 25.10.2021 | 3.06 MB | faculty member | – | |
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| Biosynthesis of lipids | 25.10.2021 | 2.19 MB | faculty member | – | |
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| Complex lipids | 25.10.2021 | 3 MB | faculty member | – | |
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| Cholesterol | 25.10.2021 | 2.12 MB | faculty member | – | |
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| Amino Acid Metabolism I | 2.4.2025 | 4.38 MB | faculty member | – | |
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| Amino Acid Metabolism II | 2.4.2025 | 4.4 MB | faculty member | – | |
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| Nucleotide Metabolism | 2.4.2025 | 1.65 MB | faculty member | – | |
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| Intermediary Metabolism | 2.4.2025 | 3.71 MB | faculty member | – | |
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| Nucleic acids - Replication of DNA and Transcription | 25.10.2021 | 4.31 MB | faculty member | – | |
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| Protein synthesis | 25.10.2021 | 5.6 MB | faculty member | – | |
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| Gene expression | 25.10.2021 | 4.65 MB | faculty member | – | |
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| Methods of NA study | 25.10.2021 | 6.39 MB | faculty member | – | |
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| Biochemistry of blood | 2.4.2025 | 5.03 MB | faculty member | – | |
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| Body Fluids | 2.4.2025 | 3.13 MB | faculty member | – | |
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| Biochemistry of the liver | 2.4.2025 | 3.46 MB | faculty member | – | |
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| Metabolism of Xenobiotics | 2.4.2025 | 3.57 MB | faculty member | – | |
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| Chemical communications | 25.10.2021 | 3.48 MB | faculty member | – | |
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| Biochemistry of Kidney | 25.10.2021 | 3.59 MB | faculty member | – | |
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| Biochemistry of nerve tissue | 25.10.2021 | 4.29 MB | faculty member | – | |
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| Biochemistry of muscle | 25.10.2021 | 3.05 MB | faculty member | – | |
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| Metabolism of hard tissues | 25.10.2021 | 4.02 MB | faculty member | – | |
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| Biochemistry of digestion and nutrition | 25.10.2021 | 3.98 MB | faculty member | – | |
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| Clinical Biochemistry | 25.10.2021 | 4.17 MB | faculty member | – | |
Courses
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Keywords: respiratory chain, cytric acid cycle, glycolyse, lipids, cholesterol
citation: Mária Mareková, Marek Stupák, Katarína Dubayová, Peter Urban: Medical biochemistry - Lectures for General Medicine students. Multimedia support in the education of clinical and health care disciplines :: Portal of Pavol Jozef Šafárik University in Košice Faculty of Medicine [online] , [cit. 06. 07. 2025]. Available from WWW: https://portal.lf.upjs.sk/articles.php?aid=165. ISSN 1337-7000.