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Systemic lupus erythematosus with multiple organ complications
Systemic lupus erythematosus (SLE) is an autoimmune disease, mostly with a chronic course, that can affect almost all important organs, most commonly skin, joints, heart and vessels, kidneys, central nervous system and lungs. The disease is characterized by B-lymphocyte hyperactivity, which leads to the formation of autoantibodies predominantly directed against non-specific antigens. This case study describes a case of SLE with multiple organ complications in a 29-year-old female patient.
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Systémový lupus erythematodes s mnohopočetnými orgánovými komplikáciami
Systémový lupus erythematodes (SLE) je autoimunitné ochorenie, väčšinou s chronickým priebehom, ktoré môže postihnúť takmer všetky dôležité orgány, najčastejšie kožu, kĺby, srdce a cievy, obličky, centrálny nervový systém a pľúca. Ochorenie je charakterizované hyperaktivitou B-lymfocytov, ktorá vedie k tvorbe autoprotilátok prevažne zameraných proti orgánovo nešpecifickým antigénom. Kazuistika opisuje prípad SLE s mnohopočetnými orgánovými komplikáciami u 29-ročnej pacientky.
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