Medical Chemistry and Biochemistry

The laboratory manuals are developed to the foreign students of medicine for practical laboratory exercise and verification of knowledge from medical biochemistry. Exercises are gathered into bigger groups by topics. Exercises are arranged into weeks, in summer term (ST) and winter term (WT), like it is in Syllabus of Lectures and practical exercises (ST, WT). Students can apply their manual skill in performing of the experiments, and also train their ability in evaluation of results.

First published: Tomečková V., Kron I., Mareková M.: Practical exercises from biochemistry, Univerzita Pavla Jozefa Šafárika v Košiciach, Košice 2011, ISBN 978-80-7097-874-0.

The subject Dental Materials represents an introduction to the study of the chemical properties of materials routinely used in dentistry. The lectures are focused on selected parts of the study of metals, including noble metals and their alloys. Furthermore, attention is focused on ceramic materials, on dental cements, as well as on polymerization and substances resulting from polymerization and used in dentistry for both restorative and prosthetic purposes.

Medical Biochemistry has an irreplaceable role in study of General Medicine. The students should learn about biochemical reactions in all living systems, especially in the human body. The knowledge will help them later to diagnose and treat many diseases correctly. In firsts semester is study concentrated to metabolic processes connected with metabolism of nutrients (e.g. saccharides, lipids, proteins, nucleic acids). In second semester is teaching focused to study metabolism of organs (e.g. liver, kidney, muscles, hard tissue, skin), chemical communications and introduction to Clinical Biochemistry.

Medical Biochemistry has an irreplaceable role in study of Dental Medicine. The students should learn about biochemical reactions taking place in the human body. The knowledge will help them better understand processes take place in the mouth. In firsts semester is study concentrated to metabolic processes connected with metabolism of nutrients (e.g. saccharides, lipids, proteins, nucleic acids). In second semester is teaching focused to study metabolism of organs (e.g. liver, kidney), hard tissue and to oral biochemistry and pathobiochemistry (e.g. dental plaque, tooth decay and tartar).

The subject Medical Chemistry includes selected chapters from general, inorganic, physical, organic chemistry. Teaching focuses mainly on bioorganic chemistry, which is a static part and an introduction to the study of medical biochemistry. Knowledge of the structure and function of chemical substances and compounds, as well as their interaction and factors which can influence these interactions is very important for students of General Medicine. Medical Chemistry represent the basis especially for the study of Medical Biochemistry, Pathobiochemistry and Clinical Biochemistry.

Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm. The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.

Mavlyanov I.R., Ashirmetov A.Kh., Mavlyanov Z.I., Jarilkasinova G.J.: CYTOCHROME P-450: genetic and population aspects, Pavol Jozef Šafárik University in Košice, Košice 2017, ISBN 978-80-8152-526-1.