Serologic reactions
In diagnostics of infectious diseases direct and indirect diagnostic methods are used. Direct diagnostics allows to visualize microorganisms as agents of infection, indirect diagnostics allows to detect reactions of the macroorganism to the presence of the microorganism. Indirect diagnostics is focused on cellular immunity (skin tests), in which specific antibodies are demonstrated by serological reactions. The lecture is devoted to the explanation of basic terms (antigen, antibody, serological reaction, its course, evaluation) and the classification of serological reactions, which are used in clinical microbiology in the diagnosis of infectious disease agents. An illustrative image or procedure, reaction principle and specific examples of use are available for individual reactions.
Microbial (bacterial) genetics
Genetic information is stored in all cells in the form of a DNA, nucleic acid molecule. A segment of DNA that codes for a molecule with a specific function is a gene. It represents the basic unit of genetic information. In bacteria, DNA is most often found in the form of one chromosome and several smaller plasmids.