Internal Medicine 4 [IK/IM-G4/19]

Acid-based balance

Author: Ivana Valočiková

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Lecture for 5- year subject Internal Medicine 4. Basic knowledge of disorders of the internal environment, their cause, diagnosis and principles of treatment of metabolic and respiratory acidosis and alkalosis. Metabolic processes ► acid/base ACIDS from carbohydrates and fat metabolism (15-20 000 mmol of CO2 daily) CO2 + H2O ►H2CO3 ►(carbonic anhydrase) H + HCO3 H + Hb in RBC ►released with oxygenation in the alveoli ►reversed reaction – H2O + CO2 – exhaled in each breath.