This lecture provides an overview of inflammatory demyelinating diseases of the central nervous system, focusing on multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), and acute disseminated encephalomyelitis (ADEM). The presentation summarizes the current knowledge of their epidemiology, pathophysiology, clinical manifestations, diagnostic criteria, and differential diagnosis.
Special attention is given to modern diagnostic tools, including magnetic resonance imaging, cerebrospinal fluid analysis, and antibody testing (AQP4-IgG and MOG-IgG). The lecture also discusses current therapeutic strategies, including treatment of acute relapses, disease-modifying therapies, and long-term management. Understanding the similarities and differences among these demyelinating disorders is essential for accurate diagnosis and appropriate treatment in clinical neurological practice.
| Attachment | Date | Size | Availability [?] | Clinically sensitive [?] | Licence | |
|---|---|---|---|---|---|---|
| Demyelinating disorders of the Central Nervous System | 4.3.2026 | 6.21 MB | faculty member | – |  |
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Keywords: multiple sclerosis, NMOSD, MOGAD, ADEM, demyelinating diseases, MRI, differential diagnosis
citation: Jarmila Szilasiová: MS, Multiple Sclerosis, NMOSD, MOGAD, ADEM. Multimedia support in the education of clinical and health care disciplines :: Portal of Pavol Jozef Šafárik University in Košice Faculty of Medicine [online] , [cit. 07. 03. 2026]. Available from WWW: https://portal.lf.upjs.sk/articles.php?aid=674. ISSN 1337-7000.