In theorethical part of this lecture author presented physiology of the pubertal development, differencies between girls and boys pubertal development. Special part is focused on patological development - precocious and delayed pubertal development - etiology, clinical manigestation, clinical approach a treatment posibilities.
Diabetes mellitus type I. is one of the most common autoimmune endocrinopathies in childhood. Author presented recent knowledge about definition and etiology of hyperglycaemia in childhood, focused to diabetes I. type - its pathophysiology, clinical manifestation, practical aproaches, treatment and complications.
The work present actual view of acute and chronic heart failure in children. It is devoted to incidence, symptoms, diagnostics and managment of this disease mainly for student of fith and sixth year of general medicine, but can be suitable for nurses, postgradual physicians as well. The main part of the work consists in diagnostis procedure and disesaseś managment.