Fundamentals of Immunology [FI-G]

Complement

Author: Katarína Čurová

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Complement is a system of more than 30 serum and membrane proteins. It represents part of the non-specific humoral immune response. The immune reaction is triggered after the cascade activation of complement components. The lecture explains basic terms, complement activation pathways, regulatory components of complement, basic functions, deficiencies of complement and possibilities of laboratory diagnostics of complement.