Medical Chemistry and Biochemistry

Medical Biochemistry has an irreplaceable role in study of Dental Medicine. The students should learn about biochemical reactions taking place in the human body. The knowledge will help them better understand processes take place in the mouth. In firsts semester is study concentrated to metabolic processes connected with metabolism of nutrients (e.g. saccharides, lipids, proteins, nucleic acids). In second semester is teaching focused to study metabolism of organs (e.g. liver, kidney), hard tissue and to oral biochemistry and pathobiochemistry (e.g. dental plaque, tooth decay and tartar).

The subject Medical Chemistry includes selected chapters from general, inorganic, physical, organic chemistry. Teaching focuses mainly on bioorganic chemistry, which is a static part and an introduction to the study of medical biochemistry. Knowledge of the structure and function of chemical substances and compounds, as well as their interaction and factors which can influence these interactions is very important for students of General Medicine. Medical Chemistry represent the basis especially for the study of Medical Biochemistry, Pathobiochemistry and Clinical Biochemistry.

The subject Medical Chemistry includes selected chapters from general, inorganic, physical and organic chemistry. Teaching focuses mainly on bioorganic chemistry, which is a static part and an introduction to the study of medical biochemistry. Knowledge of the structure and function of chemical substances and compounds, as well as their interaction and factors which can influence these interactions is important for students of Dental Medicine. We focused for information about dental materials, auxiliary dental materials and to the importance of the polymerisation in dentistry.

Knowledge of the structure and function of chemical substances and compounds, as well as their interactions and factors which can influence these interactions are very important for study Medical Chemistry and Biochemistry. The supporting materials is based on the secondary school curriculum of chemistry, and represent the summarization of knowledge’s from high school, extended by new knowledge necessary especially for the subsequent study of medical biochemistry. The repetitorium is divided into several chapters and represents a summary of knowledge focused mainly on bioorganic chemistry, including structures, nomenclature and typical reactions.

Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm. The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.

Mavlyanov I.R., Ashirmetov A.Kh., Mavlyanov Z.I., Jarilkasinova G.J.: CYTOCHROME P-450: genetic and population aspects, Pavol Jozef Šafárik University in Košice, Košice 2017, ISBN 978-80-8152-526-1.